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Which magnesium should you take?
13 sept 20264 min de lectura

Which magnesium should you take?

You’re standing in the supplement aisle, phone out, comparing two bottles of magnesium. One says glycinate, one says oxide, and there’s citrate and malate further down the shelf, all a few dollars apart. They’re all magnesium. So why are there eight of them, and which one goes in the basket? 

Most people grab whichever is cheapest, or whichever a video was selling. Then, a few days later, sometimes: why did this one upset my stomach?

Here’s the reassuring part. The forms aren’t as different as the shelf makes them look. Where they differ, it comes down to two things: how much of the magnesium your body can use, and how easy it is on your stomach. Keep those in mind and the shelf starts to make sense.

First, what "inorganic" even means

The word sounds like a warning, but it’s just chemistry. Magnesium never comes on its own. It’s always paired with a partner, and that partner is the name on the label. Oxide, citrate, glycinate, those are all just magnesium plus whoever it showed up with.


Now, here’s what matters about that partner. Before your gut can absorb the magnesium, the two have to split up in water so the magnesium can leave with your body instead. Some partners are easygoing about it. They let go, and the magnesium gets absorbed. Others are the clingy type. They won’t dissolve, they won’t let go, and the magnesium never gets free, so the whole thing just passes through and out.

That’s the real difference between a form that works and one that doesn’t. Not organic versus inorganic. Just how willing the partner is to let go.³

The Three Inorganic Forms

  • Oxide, the one to skip. This is the clingiest partner of all. Oxide barely dissolves, so most of the magnesium never breaks free to be absorbed. One often-cited study measured it at about four percent,¹ and in a two-month trial it lifted people’s magnesium no more than a sugar pill did.² Worse, all that un-absorbed magnesium sitting in your gut pulls water in behind it, which is the exact way a laxative works. That’s why oxide is sold for constipation.⁴ It’s cheap and loaded with magnesium on paper, but very little of it ever reaches you.

  • Sulfate, the bath one. You might already have this in the cupboard: it’s Epsom salt. Taken by mouth it pulls water into the gut fast, so it’s sold as a saline laxative⁵ and a soak for sore muscles, not as something you take daily. Fine for the occasional need, wrong tool for keeping your magnesium topped up.

  • Chloride, the fair surprise. Here’s where the “inorganic is bad” rule falls apart. Chloride is inorganic, but it’s an easygoing partner, it dissolves and absorbs about as well as the pricier organic forms.¹ It’s proof the problem was never “inorganic.” It was oxide, specifically.


So the label matters more than the category. Skip oxide, leave sulfate for the bath, and don’t write off chloride just because it shares a shelf with them.

The Forms Worth Reaching For

Past the inorganic aisle, you get to the forms most people are after. These are the organic magnesiums, where the partner is something friendlier, usually an amino acid or an acid your body knows from food. Citrate, glycinate, malate, and a few cousins.


They’re the easygoing partners. In water they let go of the magnesium readily, so your gut can absorb it instead of most of it drifting past unused.

That same fact is why they’re kinder to your stomach. Remember what upset it with oxide: leftover magnesium sitting in the gut, dragging water in behind it. Absorb it well, and there’s little left to cause trouble. So they’re not two perks. They’re one, from both ends.

One last thing the labels won’t tell you. Among these good forms, the differences are smaller than the marketing suggests.³ So don’t overthink it. Pick one that’s well absorbed and easy on your stomach, and take it regularly.

Where that Leaves You

So the shelf is less of a maze than it looks. The next time you’re standing in front of it, you can skip the spiral of comparing eight labels. Avoid the one that barely absorbs, pick a good one that sits well with you, and let consistency do the rest. That’s the whole game.

Our own magnesium is built on three well-absorbed organic forms, malate, citrate, and glycinate, with no oxide in sight. Curious how we put it together? Take a look at our Triple Magnesium Complex & Ashwagandha.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.


References

  1. Firoz M, Graber M. Bioavailability of US commercial magnesium preparations. Magnes Res. 2001;14(4):257-262.
  2. Walker AF, Marakis G, Christie S, Byng M. Mg citrate found more bioavailable than other Mg preparations in a randomised, double-blind study. Magnes Res. 2003;16(3):183-191.
  3. Schuchardt JP, Hahn A. Intestinal absorption and factors influencing bioavailability of magnesium — an update. Curr Nutr Food Sci. 2017;13(4):260-278. doi:10.2174/1573401313666170427162740.
  4. Mori H, Tack J, Suzuki H. Magnesium oxide in constipation. Nutrients. 2021;13(2):421. doi:10.3390/nu13020421.
  5. Dupont C, Hébert G. Magnesium sulfate-rich natural mineral waters in the treatment of functional constipation — a review. Nutrients. 2020;12(7):2052. doi:10.3390/nu12072052.
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Amy Qin, PhD, RD, CDCES, Nutrition Scientist at Neumina

Amy Qin is a Nutrition Scientist at Neumina with training in both nutrition research and clinical care. She received her PhD in Nutrition and Metabolism from the University of Wisconsin-Madison and completed clinical training at Stanford Hospital and UCSF Benioff Children's Hospital.

Her work focuses on applying nutrition science to metabolism, aging, and chronic disease management in ways that are practical and personalized.