1. Magnesium
Best for : winding down and falling asleep faster.
2. Melatonin
Best for : resetting your body's clock, jet lag, late nights, shift work.
3. Ashwagandha
Best for : the nights your mind won't stop running.
4. L-theanine
Best for : taking the edge off a wired mind, tonight.
5. Glycine
Best for : dropping off faster and sleeping more deeply.
Trending, with an Asterisk
Two honorable mentions, since they're everywhere right now.
Where that Leaves You
Sleep isn't one problem with one answer. It has a lot of moving parts, your stress, your body clock, how easily you can wind down. The right nudge depends on which part is getting in your way.
References
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Mah J, Pitre T. Oral magnesium supplementation for insomnia in older adults: a systematic review & meta-analysis. BMC Complement Med Ther. 2021;21(1):125. doi:10.1186/s12906-021-03297-z
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Ferracioli-Oda E, Qawasmi A, Bloch MH. Meta-analysis: melatonin for the treatment of primary sleep disorders. PLoS One. 2013;8(5):e63773. doi:10.1371/journal.pone.0063773
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Albalawi AA. Dual impact of ashwagandha: significant cortisol reduction but no effects on perceived stress, a systematic review and meta-analysis. Nutr Health. 2025;31(4):1395-1408. doi:10.1177/02601060251363647
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Cheah KL, Norhayati MN, Husniati Yaacob L, Abdul Rahman R. Effect of ashwagandha (Withania somnifera) extract on sleep: a systematic review and meta-analysis. PLoS One. 2021;16(9):e0257843. doi:10.1371/journal.pone.0257843
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Cotter J, Caddick CE, Harper JL, Ebajemito JK. Examining the effect of L-theanine on sleep: a systematic review of dietary supplementation trials. Nutr Neurosci. 2026;29(2):224-238. doi:10.1080/1028415X.2025.2556925
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Soh J, Raventhiran S, Lee JH, et al. The effect of glycine administration on the characteristics of physiological systems in human adults: a systematic review. Geroscience. 2024;46(1):219-239. doi:10.1007/s11357-023-00970-8
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Kazemi A, Shojaei-Zarghani S, Eskandarzadeh P, Hashempur MH. Effects of chamomile (Matricaria chamomilla L.) on sleep: a systematic review and meta-analysis of clinical trials. Complement Ther Med. 2024;84:103071. doi:10.1016/j.ctim.2024.103071
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Shinjyo N, Waddell G, Green J. Valerian root in treating sleep problems and associated disorders, a systematic review and meta-analysis. J Evid Based Integr Med. 2020;25:2515690X20967323. doi:10.1177/2515690X20967323








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